Analytical chemistry

Just finished a fun session of HPLC calibration!  Time to unwind and rambler a bit about my day.

Play remember all HPLC calibration link given below freeHeadline: Stop Memorizing HPLC SOPs. Start Mastering Them. 🎮🧪We’ve all spent hours…

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Dissolution investigation

In pharmaceutical quality control, when a product fails the S1 stage of dissolution (like the 78% result in your example),…

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FDA Propose Rule That Would Help Hold Foreign Tobacco Manufacturers Accountable, Protect Public Health

product dimensions. For e-cigarettes, manufacturers would also need to provide specifications such as e-liquid volume, battery capacity, and wattage.  To…

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RCA (ROOT CAUSE ANALYSIS) IN PHARMACEUTICAL INDUSTRIES

RCA (ROOT CAUSE ANALYSIS) IN PHARMACEUTICAL INDUSTRIES AS PER REGULATORY REQUIREMENTS 1. PROBLEM IDENTIFICATION What Happens Clearly define the deviation,…

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summary of global nitrosamine regulations FDA, EMA, ANVISA, SWISSMEDC, HEALTHCANDA.

* Nitrosamines are trace chemical impurities. * They are classified as probable human carcinogens. * Global agencies require a strict…

3 weeks ago

Understanding Analytical Method Validation: Interference and Specificity

Specificity This concept is essential in scientific analysis. When you create a method to measure something (like a drug or…

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Troubleshooting Retention Time Shift in HPLC: Causes, Solutions, and Best Practices

If you run high-performance liquid chromatography (HPLC) assay, you know that consistency is everything. In a validated method, your retention…

1 month ago

Maximizing Efficiency in Modern Quality Control Labs

Operational excellence is demanded by modern quality control laboratories. Every single day, high testing volumes are managed by laboratory analysts.…

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Key FDA Updates (Late May–Early June 2026)

The FDA’s latest updates (June 2026) include several new drug approvals, safety warnings on hidden ingredients in supplements, and upcoming…

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Method validation pharma environment

​Goal of Validation: Analytical validation proves that a testing method works correctly for its intended use. ​Why it Matters: Accurate…

1 month ago