DST is primary standard and it is stable up to 150 degree Centigrade. It release free water molecules easily when reacts with KF reagent.DST is easily soluble in methanol. This DST has 15.66% water molecules so we can easily calculate and standardize the KF reagent. We use the factorof DST the compound which has less than 1% of moisture.Water i.e 100% water molecules. But we must use 100% pure water there should absent dissolved salts and anymore. This method is not 100% accurate like DST. So generally We use the factor of water for the compound which has more than 1% of moisture.1water molecule approximately equal to 5mg of KFR.
Play remember all HPLC calibration link given below freeHeadline: Stop Memorizing HPLC SOPs. Start Mastering…
In pharmaceutical quality control, when a product fails the S1 stage of dissolution (like the…
product dimensions. For e-cigarettes, manufacturers would also need to provide specifications such as e-liquid volume,…
RCA (ROOT CAUSE ANALYSIS) IN PHARMACEUTICAL INDUSTRIES AS PER REGULATORY REQUIREMENTS 1. PROBLEM IDENTIFICATION What…
* Nitrosamines are trace chemical impurities. * They are classified as probable human carcinogens. *…
Specificity This concept is essential in scientific analysis. When you create a method to measure…