by maheshbhuva | Oct 10, 2025 | Analytical Chemistry, Analytical method development hplc,, Method validation, Quality control (QC), wet lab
Specificity analytical method validation creative way to understand Imagine analytical method validation as building a highly specialized “detection machine” for a specific target. Specificity is about ensuring your machine only detects your intended...
by maheshbhuva | Jul 26, 2025 | Analytical Chemistry, Quality control (QC), Titration, wet lab
Imagine you’re a detective, and your mission is to find out exactly how much of a sneaky, hidden chemical called an “oxidizing agent” is present in a mysterious solution. You can’t see it, you can’t smell it, but you know it’s...
by maheshbhuva | Jul 5, 2025 | Analytical Chemistry, karl Fischer titration, Molarity, Normality, Pharmaceutical interview,, Potentiometric Titration, Quality control (QC), wet lab
“Care before use” in Karl Fischer titration refers to the crucial steps and considerations taken before starting the actual titration process to ensure accurate, reliable, and safe results. Given that Karl Fischer titration is highly sensitive to moisture,...
by maheshbhuva | Apr 30, 2025 | Analytical Chemistry, Quality control (QC), stability, wet lab
1. Charging Samples to a Stability Study (Initiation):In the pharmaceutical industry, “charging” samples to a stability study refers to the process of formally placing representative samples of a drug substance or drug product into controlled storage...
by maheshbhuva | Mar 2, 2024 | wet lab
Instrument measurements viscosity call rheometer They are Different types 1) DV2T Touch Screen Viscometer2) DV2T EXTRA Touch Screen Viscometer3) CAP1000 Viscometer4) Cone Plate Wells Brookfield Viscometer5) Falling Ball ViscometerClassical instrumentU -tube(Ostwald...
by maheshbhuva | Jan 13, 2023 | Analytical Chemistry, wet lab
The analyte is typically an acid or a base. The titration is performed by adding a measured volume of the standard solution to the sample solution, and then measuring the resulting change in the electrical potential (potential) of the solution. Quality control...