by maheshbhuva | Feb 8, 2025 | Analytical Chemistry, Analytical method development hplc,, Hplc, Quality control (QC)
HPLC (High-Performance Liquid Chromatography) method development is a critical process in analytical chemistry, involving the creation of a precise and reliable method for separating, identifying, and quantifying the components of a mixture.Here’s an overview of...
by maheshbhuva | Jun 23, 2024 | ppm
Parts per million (ppm) is a way of expressing very dilute concentrations of substances. To calculate ppm, you can use the following formulas depending on what information you have. Practical Notes For dilute aqueous solutions, 1 ppm is roughly equal to...
by maheshbhuva | May 13, 2024 | Analytical Chemistry, Analytical method development hplc,, Method validation, Quality control (QC)
Type of analytical procedure validated Identification tests. Quantitative tests for impurities’ content. Limit tests for the control of impurities. Quantitative tests of the active moiety in samples of drug substance or drug product or other selected...
by maheshbhuva | Jul 28, 2023 | 621 USP CHAPTER, Analytical Chemistry, Hplc
What is update change Definitions Here Definitions and chromatograms both unified and give title Definitions Give method dwell volume determine being added Definitions add definitions size-exclusion chromatography  (Distribution constant, Retention time of an...
by maheshbhuva | Jul 25, 2023 | Glassware
In the pharmaceutical industry, glassware is also classified based on its quality and accuracy, much like the Class A and Class B classifications commonly used in laboratory glassware. The classification of glassware in pharma is typically based on standards set by...
