All chapter are use full for ADJUSTMENT of chromatography, TLC etc
In such case some questions arias that
Why adjustment in chromatography ?
How adjustment justified ?
Adjust chromatography
If your method is validated and method are submitted in DMF so
[Different lab may different working processer different instrument, column manufacture different may be fail in sst which may mention in monograph such case ]
a. Meet system suitability criteria
b. Meet relevant performance characteristics (resolution, Rt, Palt count etc(column manufacture different such case)
c. why sst or monograph condition not achieved in your labÂ
i. Change in Instrument /equipment
ii. Change column manufactureÂ
iii. Change in reagent /chemicals
iv. Different in operation (one lab to another lab)
How adjustment justified
a. By verified SST
b. By verified any other relevant performance characteristicÂ
3. Important considerationsÂ
a. Change other those indicated in gc<621> revalidation of procedure
b. Once adjusted, procedure can’t be re-adjusted with without re-validationÂ
c. Cumulative effect must be evaluated Â
Â
- XENON CHEM LLP Gujarat jobs for Production QC QA store Utility Department apply nowXENON CHEM LLP- DAHEJ Mfg. of Agro Chemical & Intermediates REQUIRED Positions Qualification Exp. in Yrs. 1. Head – QC & QA B.Sc./M.Sc. 10-15 2. Chemist – QC & QA B.Sc./M.Sc. 05-07 3. Engineer – Utility DME/BE 05-07 4. Engineer – Plant Maintenance DME/BE-Mech 05-07 5. Asst. Mgr. – Production B.Sc./M.Sc./BE-Chem. 10-15 6. Executive – […]
- Matangi Industries LLP Gujarat jobs for Multiple Vacancy in multiple Department apply nowmatangi Matangi Industries LLP a Fast growing Chemical Manufacturing Company Invites applications for its new plant for below mentioned requirement… 1. Head HR & Admin – (MHRM/PGDM, BSW/MSW, BLW/MLW, MBA in HR) (Minimum 20 years of experience in any Manufacturing Industries.) 2. Manager Accounts – (Preferred CA/MBA/ Inter CA) (Minimum 5 years of experience in […]
- Sun Pharmaceutical Industries Limited is conducting Walk-In Interviews for Multiple Positions for QC / QA / Production / Microbiology / Warehouse on 13th August, 2023 (Sunday) at BADDI.Job description:Qualification: B.Sc, M.Sc, B.Pharm, M.Pharm, B.A, B.Com, 10+2, Diploma, ITIExperience : 01-06 yearsRole: Technician / Officer / Sr. OfficerJob Location: BADDIDepartment: QC / QA / Production / Microbiology / Warehouse Time and Venue Details: Date: 13th August, 2023Time: 09:00AM to 4:00PMVenue: Sun Pharmaceutical Industries Limited, Baddi Note- Sun Pharma does not seek payment of […]
- ONEIRO lifecare Gujarat interview in 12th August 2023 jobs for Production Quality Control ADL R&D Department check nowONEIRO lifecare Walk In Interview Officer/Executive – ADL HPLC,GC-HS, Wet Lab and documentation Qualification: M. Sc/ B. Sc Experience: 1 to 5 Years Jr. Officer-Sr. Officers – R & D (Organic Synthesis & PD Lab) Research Bench work & documentation Qualification: M. Sc/ B. Sc Experience: 1 to 5 Years WE ARE HIRING Officer/Sr. Officer […]
- Milan Laboratories Ltd Bharuch Interview in 06th August 2023 for Production Department Quality Assurance Department Packing Department Warehouse Department Instrumentation Department etc check nowWalk in Interview www.milanlabs.com MILAN LABORATORIES (INDIA) PVT. LTD. Dahej, Gujarat Leading Pharmaceutical Manufacturer and Exporter from India. An ISO 9001:2015, cGMP, USFDA, UNICEF & UK-MHRA-Certified company, is a Govt. Recognized Star Export House and recipient of awards for outstanding export and other national awards. Production Officer-OSD Production Officer-QAMS 2-3 Years experience in core production […]
- Job alert
- Intas Pharmaceuticals walk in interview for OFFICER,SENIOR OFFICER ASSOCIATE, EXECUTIVE positions @ AhmedabadIntas Pharmaceuticals walk in interview Join a leading global pharmaceutical organisation About us: Intas is one of the leading multinational pharmaceutical formulation development, manufacturing and marketing companies in the world. Today, Intas is present in more than 85 countries worldwide and is growing at 20% CAGR. Around 70% of its revenues come from the international […]
- Ind-Swift Limited walk in interview for Quality control, Quality Assurance, production, packing DepartmentsInd-Swift Limited For Jawaharpur, Formulation Site (Derabassi) About us: Ind-Swift Limited – Jawaharpur, Derabassi is the Ace unit of Ind-Swift Limited, was created in the year 2005 with an aim to globalize the Ind-Swift brand for finished dosage forms. We are a 100% Export Oriented Formulation Unit dealing in regulated markets having approval like MHRA, […]
- 621 no chapter chromatography was update at on date 1-dec-2022What is update change Definitions Here Definitions and chromatograms both unified and give title Definitions Give method dwell volume determine being added Definitions add definitions size-exclusion chromatography  (Distribution constant, Retention time of an unretained compound, Total mobile phase time) Also other definitions plate height, reduced plate height, plate number etc In TLC – resolution calculation […]
- Difference class A and class b glassware use in laboratoryThe terms “Class A” and “Class B” are commonly used to describe different types of glassware in laboratory settings, particularly for volumetric measuring. These classes have specific standards and tolerances, and they serve different purposes. Here’s the difference between Class A and Class B glassware: Class A Glassware: Class A glassware is of higher precision […]
- Describe glassware types used in laboratoryLaboratories use various types of glassware to perform experiments, conduct measurements, and handle substances safely. Some common types of glassware used in laboratories include: Beakers: Cylindrical containers with a flat bottom and a spout used for holding and mixing liquids. They come in various sizes. Erlenmeyer Flasks: Conical-shaped flasks with a flat bottom and a […]
- Type of Glassware use in pharmaceutical and chemical, pasticised industryIn the pharmaceutical industry, glassware is also classified based on its quality and accuracy, much like the Class A and Class B classifications commonly used in laboratory glassware. The classification of glassware in pharma is typically based on standards set by regulatory authorities like the United States Pharmacopeia (USP) and the European Pharmacopoeia (Ph. Eur.). […]
- Latest pharmacopoeiaUSP 44-NF 39, which became official on November 1, 2021.
- GC (gas chromatography)- Detector (17 types) in between 5 detector use pharma1. CCD – Catalytic Combustion Detector 2. TCD – Thermal Conductivity Detector 3. FID – Flame Ionization Detector 4. DELCD – Dry Electrolytic Conductivity Detector 5. FID/DELCD – combination Flame Ionization Detector and Dry Electrolytic Conductivity Detector 6. HID – Helium Ionization Detector 7. PID – Photo Ionization Detector 8. NPD – Nitrogen-Phosphorus Detector 9. NPD/DELCD – combination Nitrogen-Phosphorus Detector and Dry Electrolytic Conductivity Detector (discontinued) 10. TID – Thermal Ionization Detector 11. FPD […]
- Type of Compartment of HPLC & GC ?HPLC Going into more detail, HPLC consists of a variety of components, including a solvent delivery pump, a degassing unit, a sample injector, a column oven, a detector, and a data processor. GC GC uses an inert or unreactive carrier gas as the mobile phase, and the stationary phase is generally a thin layer of liquid. As […]
- TORRENT PHARMA – Walk-In Interviews For QC, QA, Manufacturing, Packing, Engineering Ahmedabad
- 60 Openings @ Sri Krishna Pharma – Multiple Vacancies for B.Sc, M.Sc, B.Pharm, M.Pharm, B.E, B.Tech, ITI, Inter, SSC Candidates – QA / Production / Operational Excellence (TSD) Departments – Apply NowDear Job Seekers , Greetings from Sri Krishna Pharma Looking For Quality Assurance For API , OSD, Nutra Divisions Location : Hyderabad (Uppal ,Nacharam,Bollaram, Shamshabad) ,Solapur Units The incumbent will have following Skill Set Desired Candidate Profile Please share your profile for jayakishore.gollapalli@srikrishnapharma
- TORRENT PHARMA – Walk-In Interviews For QC, QA, Manufacturing, Packing, EngineeringTorrent Pharma, a renowned pharmaceutical company, is conducting walk-in interviews for various positions in Quality Control (QC), Quality Assurance (QA), Manufacturing, Packing, Engineering, and other departments. This presents a great opportunity for individuals looking to join a leading player in the pharmaceutical industry. The interviews will be held on June 11, 2023, at Hotel SUN […]
- Lupin Limited Ahmedabad interview in 11th June 2023 for Production Department Quality Control Department IPQA etc check nowHiring for Lupin Limited – Nagpur for Injectable Facility An innovation led transnational pharmaceutical company is looking for bright professionals for its State of art Injectable Manufacturing Facility at MIHAN Nagpur, (Maharashtra) for the following Walk-in Interview @ Ahmedabad Interview Date: 11th June 2023 (Sunday) LUPINpositions: Interview Time: 9.30 am to 3.00 PM Venue – […]
- How to Re-test defined in finish product in pharmaIn the pharmaceutical industry, a “finished product retest” refers to the process of evaluating a sample from a previously manufactured and packaged pharmaceutical product to assess its quality, safety, and efficacy. The purpose of the retest is to ensure that the product remains within the specified standards and meets all the required regulatory guidelines. Here […]